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Extracellular DNA within a Nontypeable Haemophilus influenzae-Induced Biofilm Binds Human Beta Defensin-3 and Reduces Its Antimicrobial Activity

Biofilms formed by nontypeable Haemophilus influenzae (NTHI) are associated with multiple chronic infections of the airway, including otitis media. Extracellular DNA (eDNA) is part of the biofilm matrix and serves as a structural component. Human β-defensin-3 (hBD-3) is a cationic antimicrobial host...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jones, Eric A., McGillivary, Glen, Bakaletz, Lauren O.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: S. Karger AG 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640559/
https://ncbi.nlm.nih.gov/pubmed/22922323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000339961
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