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A Novel Role for c-Myc in G Protein-Coupled Receptor Kinase 4 (GRK4) Transcriptional Regulation in Human Kidney Proximal Tubule Cells*
The G coupled-protein receptor kinase 4 (GRK4) negatively regulates the dopaminergic system by desensitizing the dopamine-1-receptor (D(1)R). The expressional control of GRK4 has not been reported, but here, we show that the transcription factor c-Myc binds to the promoter of GRK4 and positively reg...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640476/ https://ncbi.nlm.nih.gov/pubmed/23509080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00321 |
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