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Structural biology of retroviral DNA integration
Three-dimensional macromolecular structures shed critical light on biological mechanism and facilitate development of small molecule inhibitors. Clinical success of raltegravir, a potent inhibitor of HIV-1 integrase, demonstrated the utility of this viral DNA recombinase as an antiviral target. A va...
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| Main Authors: | , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2011
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640404/ https://ncbi.nlm.nih.gov/pubmed/21216426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.12.008 |
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