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A role for TNFα in intervertebral disc degeneration: a non-recoverable catabolic shift

This study examines the effect of TNFα on whole bovine intervertebral discs in organ culture and its association with changes characteristic of intervertebral disc degeneration (IDD) in order to inform future treatments to mitigate the chronic inflammatory state commonly found with painful IDD. Pro-...

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Autors principals: Purmessur, D., Walter, BA., Roughley, PJ., Laudier, DM., Hecht, AC., Iatridis, JC.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640343/
https://ncbi.nlm.nih.gov/pubmed/23438440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.02.034
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