REDUCED TISSUE OSMOLARITY INCREASES TRPV4 EXPRESSION AND PRO-INFLAMMATORY CYTOKINES IN INTERVERTEBRAL DISC CELLS

The mechanical behaviour and cellular metabolism of intervertebral discs (IVDs) and articular cartilage are strongly influenced by their proteoglycan content and associated osmotic properties. This osmotic environment is a biophysical signal that changes with disease and may contribute to the elevat...

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Detalhes bibliográficos
Publicado no:Eur Cell Mater
Main Authors: Walter, B.A., Purmessur, D, Moon, A., Occhiogrosso, J., Laudier, D.M., Hecht, A.C., Iatridis, J.C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072776/
https://ncbi.nlm.nih.gov/pubmed/27434269
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