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Dynamic and Static Overloading Induce Early Degenerative Processes in Caprine Lumbar Intervertebral Discs

Mechanical overloading of the spine is associated with low back pain and intervertebral disc (IVD) degeneration. How excessive loading elicits degenerative changes in the IVD is poorly understood. Comprehensive knowledge of the interaction between mechanical loading, cell responses and changes in th...

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Auteurs principaux: Paul, Cornelis P. L., Schoorl, Tom, Zuiderbaan, Hendrik A., Zandieh Doulabi, Behrouz, van der Veen, Albert J., van de Ven, Peter M., Smit, Theo H., van Royen, Barend J., Helder, Marco N., Mullender, Margriet G.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640099/
https://ncbi.nlm.nih.gov/pubmed/23638074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062411
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