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Dynamic and Static Overloading Induce Early Degenerative Processes in Caprine Lumbar Intervertebral Discs

Mechanical overloading of the spine is associated with low back pain and intervertebral disc (IVD) degeneration. How excessive loading elicits degenerative changes in the IVD is poorly understood. Comprehensive knowledge of the interaction between mechanical loading, cell responses and changes in th...

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Detalhes bibliográficos
Main Authors: Paul, Cornelis P. L., Schoorl, Tom, Zuiderbaan, Hendrik A., Zandieh Doulabi, Behrouz, van der Veen, Albert J., van de Ven, Peter M., Smit, Theo H., van Royen, Barend J., Helder, Marco N., Mullender, Margriet G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640099/
https://ncbi.nlm.nih.gov/pubmed/23638074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062411
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