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Antifungal Activity of Fused Mannich Ketones Triggers an Oxidative Stress Response and Is Cap1-Dependent in Candida albicans
We investigated the antifungal activity of fused Mannich ketone (FMK) congeners and two of their aminoalcohol derivatives. In particular, FMKs with five-membered saturated rings were shown to have minimum inhibitory concentration (MIC(90)s) ranging from 0.8 to 6 µg/mL toward C. albicans and the clos...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3639977/ https://ncbi.nlm.nih.gov/pubmed/23646117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062142 |
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