Rapid, scalable and highly automated HLA genotyping using next-generation sequencing: a transition from research to diagnostics

BACKGROUND: Human leukocyte antigen matching at allelic resolution is proven clinically significant in hematopoietic stem cell transplantation, lowering the risk of graft-versus-host disease and mortality. However, due to the ever growing HLA allele database, tissue typing laboratories face substant...

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Autors principals: Danzer, Martin, Niklas, Norbert, Stabentheiner, Stephanie, Hofer, Katja, Pröll, Johannes, Stückler, Christina, Raml, Edeltraud, Polin, Helene, Gabriel, Christian
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Methodology Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639865/
https://ncbi.nlm.nih.gov/pubmed/23557197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-221
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