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Pathogenicity of Yersinia pestis Synthesis of 1-Dephosphorylated Lipid A

Synthesis of Escherichia coli LpxL, which transfers a secondary laurate chain to the 2′ position of lipid A, in Yersinia pestis produced bisphosphoryl hexa-acylated lipid A at 37°C, leading to significant attenuation of virulence. Our previous observations also indicated that strain χ10015(pCD1Ap) (...

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Main Authors: Sun, Wei, Six, David A., Reynolds, C. Michael, Chung, Hak Suk, Raetz, Christian R. H., Curtiss, Roy
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639600/
https://ncbi.nlm.nih.gov/pubmed/23357387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01403-12
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