The Contraceptive Depot Medroxyprogesterone Acetate Impairs Mycobacterial Control and Inhibits Cytokine Secretion in Mice Infected with Mycobacterium tuberculosis

The contraceptive depot medroxyprogesterone acetate (DMPA), with progestin as the single active compound, possesses selective glucocorticoid activity and can alter the expression of glucocorticoid receptor-regulated genes. We therefore propose that pharmacological doses of DMPA used for endocrine th...

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Библиографические подробности
Главные авторы: Kleynhans, Léanie, Du Plessis, Nelita, Allie, Nasiema, Jacobs, Muazzam, Kidd, Martin, van Helden, Paul D., Walzl, Gerhard, Ronacher, Katharina
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
Предметы:
Host Response and Inflammation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639598/
https://ncbi.nlm.nih.gov/pubmed/23381991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01189-12
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