The Contraceptive Depot Medroxyprogesterone Acetate Impairs Mycobacterial Control and Inhibits Cytokine Secretion in Mice Infected with Mycobacterium tuberculosis

The contraceptive depot medroxyprogesterone acetate (DMPA), with progestin as the single active compound, possesses selective glucocorticoid activity and can alter the expression of glucocorticoid receptor-regulated genes. We therefore propose that pharmacological doses of DMPA used for endocrine th...

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Main Authors: Kleynhans, Léanie, Du Plessis, Nelita, Allie, Nasiema, Jacobs, Muazzam, Kidd, Martin, van Helden, Paul D., Walzl, Gerhard, Ronacher, Katharina
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
主題:
Host Response and Inflammation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639598/
https://ncbi.nlm.nih.gov/pubmed/23381991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01189-12
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