Staphylococcus aureus Nuclease Is an SaeRS-Dependent Virulence Factor

Several prominent bacterial pathogens secrete nuclease (Nuc) enzymes that have an important role in combating the host immune response. Early studies of Staphylococcus aureus Nuc attributed its regulation to the agr quorum-sensing system. However, recent microarray data have indicated that nuc is un...

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Detalles Bibliográficos
Autores principales: Olson, Michael E., Nygaard, Tyler K., Ackermann, Laynez, Watkins, Robert L., Zurek, Oliwia W., Pallister, Kyler B., Griffith, Shannon, Kiedrowski, Megan R., Flack, Caralyn E., Kavanaugh, Jeffrey S., Kreiswirth, Barry N., Horswill, Alexander R., Voyich, Jovanka M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
Materias:
Molecular Pathogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639593/
https://ncbi.nlm.nih.gov/pubmed/23381999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01242-12
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