Deacetylation of p53 induces autophagy by suppressing Bmf expression

Interferon γ (IFN-γ)–induced cell death is mediated by the BH3-only domain protein, Bik, in a p53-independent manner. However, the effect of IFN-γ on p53 and how this affects autophagy have not been reported. The present study demonstrates that IFN-γ down-regulated expression of the BH3 domain-only...

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Autors principals: Contreras, Amelia U., Mebratu, Yohannes, Delgado, Monica, Montano, Gilbert, Hu, Chien-an A., Ryter, Stefan W., Choi, Augustine M.K., Lin, Yuting, Xiang, Jialing, Chand, Hitendra, Tesfaigzi, Yohannes
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2013
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639396/
https://ncbi.nlm.nih.gov/pubmed/23629966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201205064
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