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Effects of GC Bias in Next-Generation-Sequencing Data on De Novo Genome Assembly
Next-generation-sequencing (NGS) has revolutionized the field of genome assembly because of its much higher data throughput and much lower cost compared with traditional Sanger sequencing. However, NGS poses new computational challenges to de novo genome assembly. Among the challenges, GC bias in NG...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3639258/ https://ncbi.nlm.nih.gov/pubmed/23638157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062856 |
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