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MicroRNA-146a Is Upregulated by and Negatively Regulates TLR2 Signaling

TLR signaling is a crucial component of the innate immune response to infection. MicroRNAs (miRNAs) have been shown to be upregulated during TLR signaling. Specifically, microRNA-146a (miR-146a) plays a key role in endotoxin tolerance by downregulating interleukin-1 receptor-associated kinase 1 (IRA...

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書目詳細資料
Main Authors: Quinn, Edel M., Wang, Jiang Huai, O’Callaghan, Grace, Redmond, H. Paul
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639252/
https://ncbi.nlm.nih.gov/pubmed/23638011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062232
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