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MicroRNA-146a Is Upregulated by and Negatively Regulates TLR2 Signaling
TLR signaling is a crucial component of the innate immune response to infection. MicroRNAs (miRNAs) have been shown to be upregulated during TLR signaling. Specifically, microRNA-146a (miR-146a) plays a key role in endotoxin tolerance by downregulating interleukin-1 receptor-associated kinase 1 (IRA...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3639252/ https://ncbi.nlm.nih.gov/pubmed/23638011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062232 |
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