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Mechanistic Role of MicroRNA-146a in Endotoxin-Induced Differential Cross-Regulation of TLR Signaling

Human TLRs are critical sensors for microbial components leading to the production of proinflammatory cytokines that are controlled by various mechanisms. Monocytes pretreated with LPS exhibit a state of hyporesponsiveness, referred to as cross-tolerance, to both homologous and heterologous ligands,...

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Hlavní autoři: Nahid, Md A., Satoh, Minoru, Chan, Edward K. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608687/
https://ncbi.nlm.nih.gov/pubmed/21178010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002311
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