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Pro-fibrotic Activities for Matrix Metalloproteinase-8 During Bleomycin-mediated Lung Injury()
Matrix metalloproteinase-8 (MMP-8) is a potent interstitial collagenase thought to be expressed mainly by PMNs. To determine whether Mmp-8 regulates lung inflammatory or fibrotic responses to bleomycin, we delivered bleomycin by the intratracheal (IT) route to wild type (WT) vs. Mmp-8(−/−) mice and...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3639121/ https://ncbi.nlm.nih.gov/pubmed/23487425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201043 |
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