Suppression of STIM1 inhibits human glioblastoma cell proliferation and induces G0/G1 phase arrest

BACKGROUND: Depletion of calcium (Ca(2+)) from the endoplasmic reticulum (ER) activates the ubiquitous store-operated Ca(2+) entry (SOCE) pathway which sustains long-term Ca(2+) signals and is critical for cellular functions. Stromal interacting molecule 1 (STIM1) serves a dual role as an ER Ca(2+)...

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Autors principals: Li, Guilin, Zhang, Zhenxing, Wang, Renzhi, Ma, Wenbin, Yang, Ying, Wei, Junji, Wei, Yanping
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639102/
https://ncbi.nlm.nih.gov/pubmed/23578185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-20
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