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Reduced Arylsulfatase B Activity in Leukocytes from Cystic Fibrosis Patients

The enzyme Arylsulfatase B (ARSB; N-acetylgalactosamine-4-sulfatase) removes 4-sulfate groups from chondroitin-4-sulfate and dermatan sulfate and is required for the degradation of these sulfated glycosaminoglycans (GAGs). Since these GAGs accumulate in patients with Cystic Fibrosis (CF), we investi...

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Detalhes bibliográficos
Main Authors: Sharma, Girish, Burke, Jenifer, Bhattacharyya, Sumit, Sharma, Neha, Katyal, Shivani, Park, R. Lucy, Tobacman, Joanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638799/
https://ncbi.nlm.nih.gov/pubmed/22550062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ppul.22567
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