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Self-assembly of protein aggregates in ageing disorders: the lens and cataract model

Cataract, neurodegenerative disease, macular degeneration and pathologies of ageing are often characterized by the slow progressive destabilization of proteins and their self-assembly to amyloid-like fibrils and aggregates. During normal cell differentiation, protein self-assembly is well establishe...

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Detalhes bibliográficos
Autor principal: Clark, John I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638398/
https://ncbi.nlm.nih.gov/pubmed/23530262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0104
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