Osteopontin Is a Novel Downstream Target of SOX9 With Diagnostic Implications for Progression of Liver Fibrosis in Humans

Osteopontin (OPN) is an important component of the extracellular matrix (ECM), which promotes liver fibrosis and has been described as a biomarker for its severity. Previously, we have demonstrated that Sex-determining region Y-box 9 (SOX9) is ectopically expressed during activation of hepatic stell...

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書誌詳細
主要な著者: Pritchett, James, Harvey, Emma, Athwal, Varinder, Berry, Andrew, Rowe, Cliff, Oakley, Fiona, Moles, Anna, Mann, Derek A, Bobola, Nicoletta, Sharrocks, Andrew D, Thomson, Brian J, Zaitoun, Abed M, Irving, William L, Guha, Indra N, Hanley, Neil A, Hanley, Karen Piper
フォーマット: Artigo
言語:Inglês
出版事項: Wiley Subscription Services, Inc., A Wiley Company 2012
主題:
Liver Biology/Pathobiology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638324/
https://ncbi.nlm.nih.gov/pubmed/22488688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25758
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