Osteopontin Is a Novel Downstream Target of SOX9 With Diagnostic Implications for Progression of Liver Fibrosis in Humans

Osteopontin (OPN) is an important component of the extracellular matrix (ECM), which promotes liver fibrosis and has been described as a biomarker for its severity. Previously, we have demonstrated that Sex-determining region Y-box 9 (SOX9) is ectopically expressed during activation of hepatic stell...

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Detalles Bibliográficos
Autores principales: Pritchett, James, Harvey, Emma, Athwal, Varinder, Berry, Andrew, Rowe, Cliff, Oakley, Fiona, Moles, Anna, Mann, Derek A, Bobola, Nicoletta, Sharrocks, Andrew D, Thomson, Brian J, Zaitoun, Abed M, Irving, William L, Guha, Indra N, Hanley, Neil A, Hanley, Karen Piper
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Liver Biology/Pathobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638324/
https://ncbi.nlm.nih.gov/pubmed/22488688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25758
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