TLR activation enhances C5a-induced pro-inflammatory responses by negatively modulating the second C5a receptor, C5L2

TLR and complement activation ensures efficient clearance of infection. Previous studies documented synergism between TLRs and the receptor for the pro-inflammatory complement peptide C5a (C5aR/CD88), and regulation of TLR-induced pro-inflammatory responses by C5aR, suggesting crosstalk between TLRs...

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Detalhes bibliográficos
Main Authors: Raby, Anne-Catherine, Holst, Benjamin, Davies, James, Colmont, Chantal, Laumonnier, Yves, Coles, Barbara, Shah, Sanjoy, Hall, Judith, Topley, Nicholas, Köhl, Jörg, Morgan, B Paul, Labéta, Mario O
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638321/
https://ncbi.nlm.nih.gov/pubmed/21630250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041350
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