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Macrophage Gene Expression and Foam Cell Formation Are Regulated by Plasminogen

BACKGROUND: Deciphering the molecular and cellular processes that govern macrophage foam cell formation is critical to understanding the basic mechanisms underlying atherosclerosis and other vascular pathologies. METHODS AND RESULTS: Here, we identify a pivotal role of plasminogen (Plg) in regulatin...

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Detalles Bibliográficos
Main Authors: Das, Riku, Ganapathy, Swetha, Mahabeleshwar, Ganapati H., Drumm, Carla, Febbraio, Maria, Jain, Mukesh K., Plow, Edward F.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638243/
https://ncbi.nlm.nih.gov/pubmed/23401155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.001214
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