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L-Type calcium channel blockers exert an anti-inflammatory effect by suppressing expression of plasminogen receptors on macrophages

L-type Ca(2+) channel (LTCC) blockers, represented by amlodipine and verapamil, are widely used anti-hypertensive drugs that also have anti-inflammatory activities. Plasminogen (Plg) is an important mediator of macrophage recruitment, and this role depends upon its interaction with Plg receptors (Pl...

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Detalhes bibliográficos
Main Authors: Das, Riku, Burke, Tim, Van Wagoner, David R., Plow, Edward F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745969/
https://ncbi.nlm.nih.gov/pubmed/19520970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.200311
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