A novel antitumor activity of deguelin targeting the insulin-like growth factor (IGF) receptor pathway via up-regulation of IGF-binding protein-3 expression in breast cancer

In this study, we investigated the antitumor effects of deguelin in several human breast cancer cells in vitro and in vivo. Deguelin inhibited cell viability and the anchorage-dependent and anchorage-independent colony formation of triple-negative (MDA-MB-231 and MDA-MB-468) and triple-positive (MCF...

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Main Authors: Suh, Young-Ah, Kim, Jai-Hyun, Sung, Myung A, Boo, Hye-Jin, Yun, Hye Jeong, Lee, Sun-Hye, Lee, Hyo-Jong, Suh, Young-Ger, Kim, Kyu-Won, Lee, Ho-Young
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638119/
https://ncbi.nlm.nih.gov/pubmed/23348700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.01.022
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