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Poly(galactaramidoamine) is an efficient cationic polymeric non-viral vector with low cytotoxicity for transfecting human embryonic kidney (HEK293) and murine macrophage (RAW264.7) cells

Poly(galactaramidoamine) (PGAA) is a cationic co-polymer of dimethyl-meso-galactarate and pentaethylenehexamine. PGAA electrostatically complexes with plasmid DNA (pDNA) to form nano-sized particles. In this study, we show that PGAA-pDNA polyplexes generate high transfection efficiencies in human em...

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Detalhes bibliográficos
Main Authors: Wongrakpanich, Amaraporn, Joshi, Vijaya B., Salem, Aliasger K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638068/
https://ncbi.nlm.nih.gov/pubmed/22235917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10837450.2011.649856
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