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The role of large pedigrees in an era of high-throughput sequencing
Rare variation is the current frontier in human genetics. The large pedigree design is practical, efficient, and well-suited for investigating rare variation. In large pedigrees, specific rare variants that co-segregate with a trait will occur in sufficient numbers so that effects can be measured, a...
Kaydedildi:
| Yazar: | |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3638020/ https://ncbi.nlm.nih.gov/pubmed/22714655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-012-1190-2 |
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