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Interplay between Drying and Stability of a TIM Barrel Protein: A Combined Simulation-Experimental Study
Recent molecular dynamics simulations have suggested important roles for nanoscale dewetting on the stability, function, and folding dynamics of proteins. Using a synergistic simulation-experimental approach on the αTS TIM barrel protein, we validate this hypothesis by revealing the occurrence of dr...
Gorde:
| Egile Nagusiak: | , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2013
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637939/ https://ncbi.nlm.nih.gov/pubmed/23293932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja310544t |
| Etiketak: |
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