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Membrane-Docking Loops of the cPLA2 C2 Domain: Detailed Structural Analysis of the Protein-Membrane Interface via Site-Directed Spin-Labeling()

C2 domains are protein modules found in numerous eukaryotic signaling proteins, where their function is to target the protein to cell membranes in response to a Ca(2+) signal. Currently, the structure of the interface formed between the protein and the phospholipid bilayer is inaccessible to high-re...

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Detalhes bibliográficos
Main Authors: Malmberg, Nathan J., Van Buskirk, David R., Falke, Joseph J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637888/
https://ncbi.nlm.nih.gov/pubmed/14609334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi035119+
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