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Characterization of the free-energy landscapes of proteins by NMR-guided metadynamics

The use of free-energy landscapes rationalizes a wide range of aspects of protein behavior by providing a clear illustration of the different states accessible to these molecules, as well as of their populations and pathways of interconversion. The determination of the free-energy landscapes of prot...

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Detalhes bibliográficos
Main Authors: Granata, Daniele, Camilloni, Carlo, Vendruscolo, Michele, Laio, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637744/
https://ncbi.nlm.nih.gov/pubmed/23572592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218350110
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