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Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model
The transformation of normal cells to malignant, metastatic tumor cells is a multistep process caused by the sequential acquirement of genetic changes. To identify these changes, we compared the transcriptomes and levels and distribution of proteins in a four-stage cell model of isogenically matched...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637701/ https://ncbi.nlm.nih.gov/pubmed/23569271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216436110 |
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