Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model

The transformation of normal cells to malignant, metastatic tumor cells is a multistep process caused by the sequential acquirement of genetic changes. To identify these changes, we compared the transcriptomes and levels and distribution of proteins in a four-stage cell model of isogenically matched...

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Detalhes bibliográficos
Principais autores: Danielsson, Frida, Skogs, Marie, Huss, Mikael, Rexhepaj, Elton, O’Hurley, Gillian, Klevebring, Daniel, Pontén, Fredrik, Gad, Annica K. B., Uhlén, Mathias, Lundberg, Emma
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637701/
https://ncbi.nlm.nih.gov/pubmed/23569271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216436110
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