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Partial loss of CovS function in Streptococcus pyogenes causes severe invasive disease

BACKGROUND: CovRS (or CsrRS) is a two-component regulatory system that regulates the production of multiple virulence factors in Streptococcus pyogenes. covS mutations are often found in isolates recovered from mice that have been experimentally infected with S. pyogenes and covS mutations enhance b...

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Autori principali: Tatsuno, Ichiro, Okada, Ryo, Zhang, Yan, Isaka, Masanori, Hasegawa, Tadao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637574/
https://ncbi.nlm.nih.gov/pubmed/23537349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-6-126
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