Rates of mutation to growth factor autonomy and tumorigenicity differ in hematopoietic stem and precursor cells expressing the multilineage colony-stimulating factor gene.

At least two separate but interdependent events are required to attain autonomous growth as a consequence of ectopic expression of the multilineage colony-stimulating factor gene in hematopoietic progenitor cells. The rate at which the second event occurs is more than 3 orders of magnitude higher in...

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I whakaputaina i:	Mol Cell Biol
Ngā kaituhi matua:	Laker, C, Kluge, N, Stocking, C, Just, U, Franz, M J, Ostertag, W, DeLamarter, J F, Dexter, M, Spooncer, E
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Taylor & Francis 1989
Ngā marau:	Research Article
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363750/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2586530/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.12.5746-5749.1989
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