Celecoxib reduces brain dopaminergic neuronaldysfunction, and improves sensorimotor behavioral performance in neonatal rats exposed to systemic lipopolysaccharide

BACKGROUND: Cyclooxygenase-2 (COX-2) is induced in inflammatory cells in response to cytokines and pro-inflammatory molecules, suggesting that COX-2 has a role in the inflammatory process. The objective of the current study was to examine whether celecoxib, a selective COX-2 inhibitor, could amelior...

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Detalhes bibliográficos
Main Authors: Kaizaki, Asuka, Tien, Lu-Tai, Pang, Yi, Cai, Zhengwei, Tanaka, Sachiko, Numazawa, Satoshi, Bhatt, Abhay J, Fan, Lir-Wan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637465/
https://ncbi.nlm.nih.gov/pubmed/23561827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-45
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