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Impact of methylene blue and atorvastatin combination therapy on the apparition of cerebral malaria in a murine model

BACKGROUND: Proveblue®, a methylene blue dye that complies with European Pharmacopoeia and contains limited organic impurities and heavy metals of recognized toxicity, showed in vitro synergy against Plasmodium falciparum when combined with atorvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl-Co...

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Bibliographic Details
Main Authors: Dormoi, Jérome, Briolant, Sébastien, Desgrouas, Camille, Pradines, Bruno
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637457/
https://ncbi.nlm.nih.gov/pubmed/23587099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-12-127
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