Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model

BACKGROUND: One of the major complications of Plasmodium falciparum infection is cerebral malaria (CM), which causes one million deaths worldwide each year, results in long-term neurological sequelae and the treatment for which is only partially effective. Statins are recognized to have an immunomod...

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Bibliografiske detaljer
Main Authors: Souraud, Jean-Baptiste, Briolant, Sébastien, Dormoi, Jérome, Mosnier, Joel, Savini, Hélène, Baret, Eric, Amalvict, Rémy, Soulard, Raoulin, Rogier, Christophe, Pradines, Bruno
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278339/
https://ncbi.nlm.nih.gov/pubmed/22233563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-13
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