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In vitro interaction of lumefantrine and piperaquine by atorvastatin against Plasmodium falciparum

BACKGROUND: There is an urgent need for the discovery of new anti-malarial drugs and combination therapy. A combinatorial approach protects each drug from the development of resistance and reduces generally the overall transmission rate of malaria. Statins, the inhibitors of 3-hydroxy-3-methylglutar...

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Main Authors: Dormoi, Jérome, Savini, Hélène, Amalvict, Rémy, Baret, Eric, Pradines, Bruno
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045961/
https://ncbi.nlm.nih.gov/pubmed/24886347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-189
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