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Dopamine receptor D1 and post-synaptic density gene variants associate with opiate abuse and striatal expression levels

Opioid drugs are highly addictive and their abuse has a strong genetic load. Dopamine-glutamate interactions are hypothesized to be important for regulating neural systems central for addiction vulnerability. Balanced dopamine-glutamate interaction is mediated through several functional associations...

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Detalhes bibliográficos
Main Authors: Jacobs, Michelle M., Ökvist, Anna, Horvath, Monika, Keller, Eva, Bannon, Michael J., Morgello, Susan, Hurd, Yasmin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637428/
https://ncbi.nlm.nih.gov/pubmed/23044706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2012.140
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