Administration of a Toll-Like Receptor 9 Agonist Decreases the Proviral Reservoir in Virologically Suppressed HIV-Infected Patients

Toll-like receptor (TLR) agonists can reactivate HIV from latently infected cells in vitro. We aimed to investigate the TLR-9 agonist, CPG 7909's in vivo effect on the proviral HIV reservoir and HIV-specific immunity. This was a post-hoc analysis of a double-blind randomized controlled vaccine...

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Main Authors: Winckelmann, Anni A., Munk-Petersen, Lærke V., Rasmussen, Thomas A., Melchjorsen, Jesper, Hjelholt, Thomas J., Montefiori, David, Østergaard, Lars, Søgaard, Ole S., Tolstrup, Martin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637371/
https://ncbi.nlm.nih.gov/pubmed/23637967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062074
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