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Resveratrol activates SIRT1 in a Lamin A-dependent manner

Human sirtuin1 (SIRT1), the closest homolog of the yeast sir2 protein, functions as an NAD+-dependent histone and non-histone protein deacetylase in several cellular processes, like energy metabolism, stress responses, aging, etc. In our recent study, we have shown that lamin A (a major nuclear matr...

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Autors principals: Ghosh, Shrestha, Liu, Baohua, Zhou, Zhongjun
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637344/
https://ncbi.nlm.nih.gov/pubmed/23439428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24061
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