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High-frequency homologous recombination between duplicate chromosomal immunoglobulin mu heavy-chain constant regions.

Homologous recombination was used in a previous study to correct a 2-base-pair deletion in the third constant domain (Cmu3) of the haploid chromosomal mu gene in a mutant hybridoma cell line by transfer of a pSV2neo vector bearing a subfragment of the normal Cmu region (M.D. Baker, N. Pennell, L. Bo...

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Bibliographic Details
Published in:Mol Cell Biol
Main Author: Baker, M D
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC363720/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2511436/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.12.5500
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