LIM-homeodomain Transcription Factor Isl-1 Mediates the Effect of Leptin on Insulin Secretion in Mice

In addition to the well known regulating effects of leptin on energy balance and glucose homeostasis through the central nervous system, circulating leptin has a direct effect on pancreatic islet and insulin secretion through its receptor (OBRb). The LIM-homeodomain transcription factor Isl-1 is exp...

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Dettagli Bibliografici
Autori principali: Chen, Juan, Fu, Rui, Cui, Yan, Li, Yu-shan, Pan, Ji-rong, Liu, Jia-li, Luo, Hao-shu, Yin, Jing-dong, Li, De-fa, Cui, Sheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Gene Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636923/
https://ncbi.nlm.nih.gov/pubmed/23504315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.450536
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