LIM-Homeodomain Transcription Factor Isl-1 Mediates Kisspeptin's Effect on Insulin Secretion in Mice

Kisspeptin and the G protein-coupled receptor 54 (GPR54) are highly abundant in the pancreas. In addition, circulating kisspeptin directly influences insulin secretion through GPR54. However, the mechanisms by which kisspeptin affects insulin release are unclear. The LIM-homeodomain transcription fa...

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Bibliografiske detaljer
Udgivet i:Mol Endocrinol
Main Authors: Chen, Juan, Fu, Rui, Cui, Yan, Pan, Jirong, Li, Yushan, Zhang, Xiaoxin, Evans, Sylvia M., Cui, Sheng, Liu, Jiali
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414806/
https://ncbi.nlm.nih.gov/pubmed/24956377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1410
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