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LIM-Homeodomain Transcription Factor Isl-1 Mediates Kisspeptin's Effect on Insulin Secretion in Mice

Kisspeptin and the G protein-coupled receptor 54 (GPR54) are highly abundant in the pancreas. In addition, circulating kisspeptin directly influences insulin secretion through GPR54. However, the mechanisms by which kisspeptin affects insulin release are unclear. The LIM-homeodomain transcription fa...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Chen, Juan, Fu, Rui, Cui, Yan, Pan, Jirong, Li, Yushan, Zhang, Xiaoxin, Evans, Sylvia M., Cui, Sheng, Liu, Jiali
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414806/
https://ncbi.nlm.nih.gov/pubmed/24956377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1410
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