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An Allelic Series at the Paired Box Gene 6 (Pax6) Locus Reveals the Functional Specificity of Pax Genes

The advent of the ocular and nervous system in metazoan evolution coincides with the diversification of a single ancestral paired box (Pax) gene into Pax6, Pax6(5a), and Pax2. To investigate the role of these Pax genes in neural development, we have generated an allelic series of knock-in models at...

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Detalhes bibliográficos
Main Authors: Carbe, Christian, Garg, Ankur, Cai, Zhigang, Li, Hongge, Powers, Andrea, Zhang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636897/
https://ncbi.nlm.nih.gov/pubmed/23515312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.436865
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