Increased activity of the Vesicular Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor TI-VAMP/VAMP7 by Tyrosine Phosphorylation in the Longin Domain

Vesicular (v)- and target (t)-SNAREs play essential roles in intracellular membrane fusion through the formation of cytoplasmic α-helical bundles. Several v-SNAREs have a Longin N-terminal extension that, by promoting a closed conformation, plays an autoinhibitory function and decreases SNARE comple...

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Autors principals: Burgo, Andrea, Casano, Alessandra M., Kuster, Aurelia, Arold, Stefan T., Wang, Guan, Nola, Sébastien, Verraes, Agathe, Dingli, Florent, Loew, Damarys, Galli, Thierry
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636883/
https://ncbi.nlm.nih.gov/pubmed/23471971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.415075
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