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Dual Role of the Metalloprotease FtsH in Biogenesis of the DrrAB Drug Transporter

This study provides the first direct evidence for the dual role of the metalloprotease FtsH in membrane protein biogenesis. Using the physiological substrate DrrAB, it is shown that FtsH is not only responsible for proteolysis of unassembled DrrB protein but also plays a much broader role in biogene...

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Bibliographic Details
Main Authors: Li, Wen, Rao, Divya K., Kaur, Parjit
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636873/
https://ncbi.nlm.nih.gov/pubmed/23504316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.441915
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