Structure and Interactions of the Human Programmed Cell Death 1 Receptor

PD-1, a receptor expressed by T cells, B cells, and monocytes, is a potent regulator of immune responses and a promising therapeutic target. The structure and interactions of human PD-1 are, however, incompletely characterized. We present the solution nuclear magnetic resonance (NMR)-based structure...

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Detalhes bibliográficos
Main Authors: Cheng, Xiaoxiao, Veverka, Vaclav, Radhakrishnan, Anand, Waters, Lorna C., Muskett, Frederick W., Morgan, Sara H., Huo, Jiandong, Yu, Chao, Evans, Edward J., Leslie, Alasdair J., Griffiths, Meryn, Stubberfield, Colin, Griffin, Robert, Henry, Alistair J., Jansson, Andreas, Ladbury, John E., Ikemizu, Shinji, Carr, Mark D., Davis, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636866/
https://ncbi.nlm.nih.gov/pubmed/23417675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.448126
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