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Antifolate drug selection results in duplication and rearrangement of chromosome 7 in Plasmodium chabaudi.

We selected lines of Plasmodium chabaudi that are resistant to high levels of the antifolate drug pyrimethamine and have shown that rearrangement and duplication of a portion of chromosome 7 has occurred in the resistant lines. This chromosomal duplication results in an increase in the chromosome nu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Cowman, A F, Lew, A M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1989
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC363670/
https://ncbi.nlm.nih.gov/pubmed/2601715
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