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Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions

Glucagon, an essential regulator of glucose homeostasis, also modulates lipid metabolism and promotes weight loss, as reflected by the wasting observed in glucagonoma patients. Recently, coagonist peptides that include glucagon agonism have emerged as promising therapeutic candidates for the treatme...

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Hlavní autoři: Habegger, Kirk M., Stemmer, Kerstin, Cheng, Christine, Müller, Timo D., Heppner, Kristy M., Ottaway, Nickki, Holland, Jenna, Hembree, Jazzminn L., Smiley, David, Gelfanov, Vasily, Krishna, Radha, Arafat, Ayman M., Konkar, Anish, Belli, Sara, Kapps, Martin, Woods, Stephen C., Hofmann, Susanna M., D’Alessio, David, Pfluger, Paul T., Perez-Tilve, Diego, Seeley, Randy J., Konishi, Morichika, Itoh, Nobuyujki, Kharitonenkov, Alexei, Spranger, Joachim, DiMarchi, Richard D., Tschöp, Matthias H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636653/
https://ncbi.nlm.nih.gov/pubmed/23305646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1116
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